Critical points, fitness, and evolution in natural and synthetic biological networks.
E. coli growing in a high lactose concentration.

Principal Investigator

Christian Ray, Assistant Professor

Computational Biology Profile

Molecular Biosciences Profile



Christian presented at Virginia Tech in the Center for Soft Matter and Biological Physics Seminar Series.


Huijing, GW, and Christian presented at MPI 2016.


Christian presented a contributed talk at q-bio 2016.


Huijing presented a poster at q-bio 2016.


The Ray lab joined CMADP with a pilot project titled, "An integrative platform for cell-resolution analysis of the acute-to-chronic transition in bacterial pathogens".


Huijing was accepted to the Tenth Annual q-bio Summer School at the University of California, San Diego campus!


Christian presented a talk at the Isaac Newton Institute's Stochastic Dynamical Systems in Biology: Numerical Methods and Applications program Advances in numerical and analytic approaches for the study of non-spatial stochastic dynamical systems in molecular biology.


Two papers accepted this week:

Cellular growth arrest and persistence from enzyme saturation
J Christian J Ray, Michelle L Wickersheim, Ameya P Jalihal, Yusuf O Adeshina, Tim F Cooper, and Gábor Balázsi

PLOS Comp Biol (2016)

Survival of phenotypic information during cellular growth transitions
J Christian J Ray

ACS Synth Biol (2016) DOI 10.1021/acssynbio.5b00229


In which we resemble Lyapunov on introducing Prof. Brian Ackley at the 2016 K-INBRE Symposium. Also introduced: three impressive trainees: [1] [2] [3].


At long last, we have updated our research and personnel pages.


New paper published:

Amino acid positions subject to multiple coevolutionary constraints can be robustly identified by their eigenvector network centrality scores
Daniel J. Parente, J. Christian J. Ray, Liskin Swint-Kruse

Proteins (2015) 83(12):2293-2306. DOI 10.1002/prot.24948


New paper published:

Stress-response balance drives the evolution of a network module and its host genome
Caleb González, Joe Christian J Ray, Michael Manhart, Rhys M Adams, Dmitry Nevozhay, Alexandre V Morozov, Gábor Balázsi

Molecular Systems Biology (2015) 11: 827. DOI 10.15252/msb.20156185


Dry Lab

Center for Computational Biology
260 MRB
2030 Becker Drive
Lawrence, KS 66045

Tel: +1 (785) 864-1506

Wet Lab

Department of Molecular Biosciences
4006 Haworth Hall
1200 Sunnyside Avenue
Lawrence, KS 66045

Tel: +1 (785) 864-3206