Critical points, fitness, and evolution in natural and synthetic biological networks.
E. coli growing in a high lactose concentration.

Principal Investigator

Christian Ray, Assistant Professor

Computational Biology Profile

Molecular Biosciences Profile



Christian presented a contributed talk at q-bio 2016.


Huijing presented a poster at q-bio 2016.


The Ray lab joined CMADP with a pilot project titled, "An integrative platform for cell-resolution analysis of the acute-to-chronic transition in bacterial pathogens".


Huijing was accepted to the Tenth Annual q-bio Summer School at the University of California, San Diego campus!


Christian presented a talk at the Isaac Newton Institute's Stochastic Dynamical Systems in Biology: Numerical Methods and Applications program Advances in numerical and analytic approaches for the study of non-spatial stochastic dynamical systems in molecular biology.


Two papers accepted this week:

Cellular growth arrest and persistence from enzyme saturation
J Christian J Ray, Michelle L Wickersheim, Ameya P Jalihal, Yusuf O Adeshina, Tim F Cooper, and Gábor Balázsi

PLOS Comp Biol (2016)

Survival of phenotypic information during cellular growth transitions
J Christian J Ray

ACS Synth Biol (2016) DOI 10.1021/acssynbio.5b00229


In which we resemble Lyapunov on introducing Prof. Brian Ackley at the 2016 K-INBRE Symposium. Also introduced: three impressive trainees: [1] [2] [3].


At long last, we have updated our research and personnel pages.


New paper published:

Amino acid positions subject to multiple coevolutionary constraints can be robustly identified by their eigenvector network centrality scores
Daniel J. Parente, J. Christian J. Ray, Liskin Swint-Kruse

Proteins (2015) 83(12):2293-2306. DOI 10.1002/prot.24948


New paper published:

Stress-response balance drives the evolution of a network module and its host genome
Caleb González, Joe Christian J Ray, Michael Manhart, Rhys M Adams, Dmitry Nevozhay, Alexandre V Morozov, Gábor Balázsi

Molecular Systems Biology (2015) 11: 827. DOI 10.15252/msb.20156185


Dry Lab

Center for Computational Biology
260 MRB
2030 Becker Drive
Lawrence, KS 66045

Tel: +1 (785) 864-1506

Wet Lab

Department of Molecular Biosciences
4006 Haworth Hall
1200 Sunnyside Avenue
Lawrence, KS 66045

Tel: +1 (785) 864-3206